منابع مشابه
How chronic stress exacerbates cancer
476 A reas of negative charge come and go on the plasma membrane, report Tony Yeung, Sergio Grinstein (Hospital for Sick Children, Toronto, Canada), and colleagues. Loss of the charged areas correlates with the loss of certain signaling proteins from the membrane and inactivation of related downstream activity. Attraction based on charge is well established for sequence-specifi c protein–protei...
متن کاملPain exacerbates chronic mild stress-induced changes in noradrenergic transmission in rats.
Depression can influence pain and vice versa, yet the biological mechanisms underlying how one influences the pathophysiology of the other remains unclear. Dysregulation of locus coeruleus-noradrenergic transmission is implicated in both conditions, although it is not known whether this effect is exacerbated in cases of co-morbid depression and chronic pain. We studied locus coeruleus activity ...
متن کاملChronic mild prenatal stress exacerbates the allergen-induced airway inflammation in rats.
The effects of chronic mild prenatal stress on leukocyte infiltration into the airways was investigated in rat offspring. The chronic prenatal stress consisted of transitory and variable changes in the rat's living conditions. Offspring at adult age were actively sensitized (day 0) and intratracheally challenged (day 14) with ovalbumin. Bronchoalveolar lavage was performed in the offspring at 4...
متن کاملChronic stress and susceptibility to skin cancer.
BACKGROUND Studies have shown that chronic stress or UV radiation independently suppress immunity. Given their increasing prevalence, it is important to understand whether and how chronic stress and UV radiation may act together to increase susceptibility to disease. Therefore, we investigated potential mediators of a stress-induced increase in emergence and progression of UV-induced squamous c...
متن کاملRepeated intermittent stress exacerbates myocardial ischemia-reperfusion injury.
Chronic stress in humans has been correlated with increased risk for ischemic heart disease. Thus experiments were conducted to determine if repeated intermittent restraint stress increased infarct size in a rat model of myocardial ischemia-reperfusion injury. Male Sprague-Dawley rats were subjected to no stress (control) or to daily restraint stress for 1-1.5 h for 8-14 days (stress protocol A...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2006
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1744rr3